Whole-genome sequencing analyses of 104 Vibrio cholerae samples from across four African countries finds isolates of the current pandemic strain exhibit concerningly high resistance to frontline antibiotics, including 96% harbouring resistance to trimethoprim and 83% to quinolones. 

Kyushu University researchers have created a novel “ACTG” naming system for human gene types, and launched the Joint Open Genome and Omics Platform 1.0 (JoGo 1.0), a global database cataloging 4.7 million gene types from more than 19,000 genes. Integrated with other public resources, the platform establishes a universal language for human gene types, empowering applications in fields such as disease research, drug development, and evolutionary biology.

A new case report shows that a quick, bedside ultrasound test can detect possible brain abscesses by identifying characteristic lesions. While not a definitive diagnostic tool, this low-cost method could help emergency departments, especially in resource-limited settings, triage patients faster for advanced scans and crucial surgery.

Metabolic dysfunction-associated steatotic liver disease (MASLD), a spectrum of liver conditions ranging from simple steatosis to steatohepatitis (MASH), fibrosis, and cirrhosis, represents a global health epidemic with no approved pharmacotherapies.