Scientists sharpen genetic maps to help pinpoint DNA changes that influence human health traits and disease risk
Peer-Reviewed Publication
Updates every hour. Last Updated: 30-May-2026 00:15 ET (30-May-2026 04:15 GMT/UTC)
Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health traits. By probing regions of DNA previously linked to disease, the work has created high resolution maps of DNA variant activity, helping pinpoint the exact changes that shape blood pressure, cholesterol levels, blood sugar and other complex human traits.
Cold Spring Harbor Laboratory Assistant Professor Benjamin Cowley and colleagues have developed an AI version of the visual cortex that’s about 500 times smaller than state-of-the-art computer vision models. Their research brings us closer to understanding how the brain processes sight and may set the stage for AI models of mental health conditions.
A team of researchers at the Icahn School of Medicine at Mount Sinai, Weill Cornell Medicine, and other institutions have uncovered a key biological explanation for why eczema so often starts in childhood. The study, in young mice, found that some types of immune cells in early-life skin are more reactive than those in adults, a difference that may help explain why children are more vulnerable to inflammation and allergic skin disease. The findings suggest that early childhood represents a critical window for immune-driven skin disease and may shed light on why eczema is often the first condition in a broader pattern of allergic disease. They were reported in the February 25 online issue of Nature [DOI: 10.1038/s41586-026-10162-x].
Reef-building stony and fire corals support a rich microbiome consisting largely of unknown species. By leveraging genetic material, ETH researchers have now managed to characterise some of these microorganisms. The microorganisms can produce natural products which could be used for medical therapies and chemical reactions. Reefs may also be home to thousands of other useful microbes which, alongside their coral hosts, are threatened with extinction.
Dennis Lal, an internationally recognized genomic scientist and health informatics leader, has been appointed as a professor with The University of Texas at Arlington and the new executive director of the Center for Innovation in Health Informatics (CIHI), where he will lead health care-scale informatics, precision health, and clinical AI initiatives.