Chronic stress fuels cancer by releasing stress mediators that remodel the tumor and stromal cells, promoting immune evasion, angiogenesis, and metastasis. A review in Science Bulletin underscores how blocking this signaling could improve outcomes and proposes stress management as a potential component of precision oncology.

A multicenter study led by Prof. Shuixing Zhang and Prof. Bin Zhang from the First Affiliated Hospital of Jinan University enrolled 246 patients with locally advanced NPC treated with immunotherapy. By applying artificial intelligence algorithms, the team extracted and selected optimal radiomic features from medical imaging to construct a predictive model.

A trailblazing Genomic Press interview with Dr. Bruce M. Cohen explores how cutting-edge brain cell technology is providing revolutionary new information on the biological origins of psychiatric disorders. Among these findings, the Harvard professor discusses discoveries on mitochondrial dysfunction that are opening novel therapeutic pathways for schizophrenia, bipolar disorder, and Alzheimer disease. In addition, his advocacy for evidence-based diagnostic models challenges century-old psychiatric frameworks, proposing specific dimensional approaches that better capture the complexities of causes, presentations, and outcomes of mental illnesses.