Healthcare leaders say generational differences about workplace flexibility, expectations of staying in the same job, burnout and transition to retirement are making it more difficult to retain doctors and nurses.

A $1.5M grant has been awarded to William Van Nostrand, co-executive director of the University of Rhode Island’s George & Anne Ryan Institute for Neuroscience and professor of pharmaceutical and biomedical sciences in the URI College of Pharmacy, to study cerebral amyloid angiopathy (CAA), a disease prevalent in the elderly population and commonly found in patients with Alzheimer's disease.

Researchers at the MRC Laboratory of Medical Sciences (LMS), Imperial College London and UCL Genetics Institute have created a detailed map of cells within breast tumours and identified distinct neighbourhoods of proliferating and dormant cells. The study, published in Genome Medicine, reveals that protective immune and connective cells surround the hibernating cancer cells, potentially shielding them from treatments. It suggests future therapies may need to target not only different cancer cell states, but also the local environments that help them survive, to both halt tumour growth and prevent cancer coming back later.

 JMIR Publications released five feature News and Perspectives articles, covering the unexpected outcomes of social media regulations in Australia, China’s AI health landscape, and how digital innovations are being used to improve health outcomes across the United States.

Protein-fortified foods are popping up everywhere, from cereal and coffee to even protein water. But a new review covering over 350 papers on protein restriction and aging—publishing July 31 in the Cell Press journal Cell Press Blue—suggests that consuming less protein could have greater health benefits and could, in some cases, extend lifespan. The authors describe how protein restriction slows aging by improving metabolism, changing how cells respond to nutrients, reducing cellular damage, and preserving healthy cell function.

About the Study: What is the potential impact of expanding alcohol screening and brief interventions in primary care on premature mortality from major alcohol-related causes of death in US adults? In this decision analytical model and microsimulation study, expanding delivery of alcohol brief interventions to an additional 8 million interventions per year was projected to reduce annual alcohol-related potential years of life lost per 100 000 adults by −51.3 (95% credible interval [CrI], −73.2 to −32.8) in men and −34.1 (CrI, −54.5 to −16.1) in women by 2030 compared with the status quo. These findings suggest that substantially expanding alcohol screening and brief interventions in primary care may reduce premature mortality and help narrow the socioeconomic gap in alcohol-related mortality in the US.

About the Study: What are the long-term trends in US nursing home closures and ownership transitions and how are facility characteristics associated with different types of operational change? In this cohort study of 33 110 US nursing home locations from 1985 to 2025, nearly half of the facilities followed simple entry-exit patterns, while approximately one-fifth remained operational despite ownership changes. Organizational restructuring, including change of ownership and within-facility capacity reconfiguration, became more common over time and was more prevalent than permanent facility closure or market exit. These findings suggest that nursing home closures often reflect broader organizational restructuring rather than true market exit, highlighting the importance of incorporating ownership transitions and capacity changes into nursing home policy and oversight.

About the Study: This Viewpoint explores how school-entry vaccine requirements provide an unusually valuable point of contact between the education system and the health care system.