Epigenetic dysregulation of PDX1 drives prostate cancer progression
Peer-Reviewed Publication
Updates every hour. Last Updated: 8-Jun-2026 03:16 ET (8-Jun-2026 07:16 GMT/UTC)
Applying new analytic methods to nearly 16,000 ancient genomes reveals natural selection has acted on hundreds, not dozens, of genes in West Eurasia over the last 10,000 years. More than half of the genes have known links to disease risk and other traits today, although it’s not yet clear what made each gene advantageous in prehistoric contexts. The work demonstrates the power of ancient DNA to illuminate human biology and medicine in addition to history.