USC researchers studying human brain tissue found an association between abnormal immature astroglia, cells that play a supporting role in brain function, and lower reasoning ability in older adults with epilepsy.

A Concordia-led study suggests that childhood home environments may influence long-term mental health in children of parents with bipolar disorder. Researchers found that less structured, predictable family environments were associated with changes in cortisol responses and more depression and anxiety symptoms in young adulthood, highlighting the potential value of family-based prevention.

Many older patients with heart failure survive hospitalization but lose independence within a year after discharge. Researchers from Japan developed a machine learning model using physical function and clinical data to predict this risk. The model outperformed a standard frailty screening tool and identified a group with low mortality but high functional decline. The findings could help clinicians prioritize rehabilitation and discharge support for patients most likely to lose independence after discharge and improve care.