In a major step forward for cancer care, researchers at ChristianaCare’s Gene Editing Institute have shown that disabling the NRF2 gene with CRISPR technology can reverse chemotherapy resistance in lung cancer. The approach restores drug sensitivity and slows tumor growth. The findings appear today in the journal Molecular Therapy Oncology.

World COPD Day is organized by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) in collaboration with health care professionals and COPD patient groups throughout the world. Its aim is to raise awareness, share knowledge, and discuss ways to reduce the burden of COPD worldwide. The 2025 theme for World COPD Day is “Short of Breath, Think COPD.” World COPD Day takes place on November 19th. This year's theme aims to emphasize that although COPD is the third leading cause of death worldwide, it is often not diagnosed correctly. COPD is a common, preventable, and treatable disease, but extensive under-diagnosis and misdiagnosis lead to patients receiving no treatment or incorrect treatment. Appropriate earlier diagnosis of COPD can have a very significant public health impact. Earlier diagnosis and treatment results in better clinical outcomes, including improvements in symptoms, lung function and quality of life.  A diagnosis of COPD should be considered in any patient who has shortness of breath, chronic cough or sputum production, a history of recurrent lower respiratory infections and/or a history of exposure to risk factors like tobacco, cooking fuels, or occupational hazards.

A 3 months study conducted in the intensive care unit (ICU) in Japan, revealed that healthcare workers experience reduced environmental satisfaction and concentration due to lack of natural light and excessive ambient noise. When designing ICUs, architects should focus on increasing natural light and mitigating noise. These factors could help enhance healthcare worker satisfaction, productivity, and quality of patient care.