This cohort study observed substantial increases in acute health care utilization, especially virtual care-seeking following the Los Angeles fires. As disruptive climate events increase, such data are essential to inform health care preparedness and response.

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have discovered that this single inherited mutation causes whole-body issues in an animal model after its immune response is sparked into action.

Although the scientists stress the research is at a relatively early stage, it is one of the first pieces of work to show that a heritable mitochondrial DNA mutation can independently remodel immune cell function and inflammatory signalling. 

It thus offers a plausible hypothesis as to why individuals with inherited primary mitochondrial disorders often experience problems with multiple organs and suffer repeated infections and sepsis. Additionally, it puts a potential target on specific links in the immune response chain that offer the greatest potential for therapeutic success.

A new evidence brief, based on a study by the Juno Evidence Alliance conducted in collaboration with CABI’s One Health Hub, has highlighted that a One Health approach is needed in research into zoonotic disease risks around the world.

If we fail to curb climate change, malaria mosquitoes could significantly expand their habitats across Africa, exposing hundreds of millions of people to a higher risk of infection.

Researchers at the University of Seville report that schizophrenia-spectrum disorders may originate in specific brain regions showing early structural damage. Using MRI-based MIND networks, they found reduced structural similarity—especially in temporal, cingulate and insular lobes—linked to worse symptoms. Affected areas showed high astrocyte and neurotransmitter presence, pointing to potential biomarkers and personalized treatments.