Article Highlights
Updates every hour. Last Updated: 28-Oct-2026 20:16 ET (29-Oct-2026 00:16 GMT/UTC)
Regional inequities in metabolic dysfunction–associated steatotic liver disease burden and care quality in high-burden settings: implications for health systems
Xia & He Publishing Inc.- Journal
- Journal of Clinical and Translational Hepatology
Korea University Ansan Hospital researchers demonstrate brain stimulation therapy improves depression and apathy in Parkinson's disease
Korea University College of Medicine- Journal
- Acta Neuropsychiatrica
CCN1 orchestrates region-specific microglial distribution in brain development
Compuscript Ltd- Journal
- Genes & Diseases
- Funder
- National Key R&D Program of China, National Natural Science Foundation of China, Shanghai Pilot Program for Basic Research, Peak Disciplines (type IV) of Institutions of Higher Learning in Shanghai
Surgery for locally advanced stage IIIB (T4N2) EGFR-mutated lung adenocarcinoma in the era of targeted therapy: a case report
Higher Education PressA 60-year-old woman with stage IIIB (T4N2) EGFR-mutated lung adenocarcinoma invading the distal trachea and superior vena cava underwent curative-intent surgery after neoadjuvant chemotherapy. The complex procedure, planned with 3D modeling, included a right upper double-sleeve bilobectomy, tracheal bifurcation sleeve resection, and SVC replacement with a xenopericardial conduit. Adjuvant osimertinib provided 35 months of recurrence-free survival. Subsequent relapse with MET amplification responded transiently to crizotinib; the patient survived 42 months post-surgery, illustrating the potential of multimodal therapy in selected patients.
- Journal
- Malignancy Spectrum
A histopathological spectrum, descriptive epidemiology and survival status of ovarian cancer cases from a tertiary cancer center in northern India: a retrospective cohort study
Higher Education PressThis retrospective cohort study evaluated the demographic profile, treatment patterns, and survival outcomes of 437 ovarian cancer patients treated at a tertiary cancer centre in Bihar, India, between January 2019 and December 2023. Most patients presented at advanced stages (III–IV, 74.6%), with serous carcinoma being the most common histotype (52.5%). Median overall survival was 22.7 months, with 1-year, 2-year, and 5-year OS rates of 68.9%, 46.5%, and 20.6%, respectively. Surgery followed by chemotherapy was associated with significantly better outcomes. Late diagnosis remains a major challenge, underscoring the need for improved screening in rural areas.
- Journal
- Malignancy Spectrum
Self‑oriented gradient ionic skins for dual‑function electromagnetic shielding and self‑powered sensing
Shanghai Jiao Tong University Journal CenterIonic skins (I-skins) integrated with high-performance electromagnetic interference (EMI) shielding, self-powering functionality, and sensitive pressure detection are critically needed for soft electronics, yet remains a considerable challenge. Herein, we report a facile diffusion-complexation strategy for fabricating self-oriented gradient MXene/polyelectrolyte hydrogels, which function effectively as self-powered I-skins with outstanding EMI shielding and pressure-sensing capabilities. A pivotal feature of our method is the concurrent coupling of two processes: osmotic pressure gradient- induced in-plane self-orientation of MXene nanosheets and diffusion-complexation reaction-induced spontaneous formation of a longitudinal charge gradient. This charge gradient endows the I-skins with a pressure-sensitive self-polarized potential, while the in-plane aligned MXene network imparts both exceptional EMI shielding performance and high-pressure sensitivity. Consequently, the resulting I-skins exhibit a high EMI shielding effectiveness of 48 dB, along with outstanding self-powered sensing capability that delivers a high sensitivity (3.067 mV kPa−1), a broad sensing range (0.05–80 kPa), a fast response time (120–130 ms), and a low detection limit for pressure (0.05 kPa). This work offers a new and scalable strategy for integrating high sensitivity, energy autonomy, and superior EMI shielding into advanced I-skins for broader applications.
- Journal
- Nano-Micro Letters
A sulfur signal helps tomato plants survive heat
Nanjing Agricultural University The Academy of ScienceAs heat waves intensify, helping crops survive sudden temperature spikes has become a practical goal for vegetable production.
- Journal
- Horticulture Research
Multiphysics modeling and analysis for dendrite problems in solid‑state lithium/sodium metal batteries
Shanghai Jiao Tong University Journal CenterThe commercialization of liquid lithium-ion batteries has revolutionized the consumer electronics industry. However, conventional lithium-ion batteries with graphite anodes and organic electrolytes are approaching their intrinsic performance limits and struggle to meet the growing demands for higher energy density, reliability, and safety in electric vehicles and large-scale energy storage. Solid-state batteries utilizing lithium or sodium metal anodes are considered promising next-generation energy storage solutions. Despite this potential, the formation of dendrites during charge–discharge cycling remains a critical challenge. Dendrite growth can initiate a destructive feedback loop of crack propagation and further dendrite intrusion, ultimately leading to battery failure and performance degradation. Previous studies have predominantly focused on single physical domains, such as electrochemical, stress, or thermal fields. However, such single-physics approach limits the understanding of dendrite evolution under realistic, coupled multiphysics conditions. This review first compares the morphological characteristics of dendrites in liquid and solid-state metal batteries. It then critically examines the key factors and predictive models of dendrite formation, initially from single-physics and subsequently from an integrated multiphysics perspective. Finally, strategies for mitigating dendrite growth via multiphysics field regulation are summarized. By establishing a comprehensive framework that integrates morphology evolution, multiphysics modeling, and suppression strategies, this work provides a foundational theoretical understanding for addressing dendrite formation in solid-state lithium and sodium metal batteries.
- Journal
- Nano-Micro Letters
Lightening tumors: AI-powered fluorescence imaging enables a new era of precise diagnosis and treatment
Chinese Society for Optical EngineeringFluorescence molecular imaging is an evolving technology for precision tumor diagnosis and therapy. By means of fluorescence probes, it enables the visualization of tumor-associated molecules, cells, or microenvironmental components, thereby facilitating the efficient identification and localization of lesions. With recent advances in the near-infrared II (NIR-II) window, targeted probes, microenvironment-responsive probes, multimodal imaging strategies, and theranostic integrated probes, fluorescence molecular imaging is shifting from a modality primarily used to “visualize lesions” toward a more comprehensive platform for tumor identification, therapy facilitation, and treatment-response monitoring. Meanwhile, artificial intelligence, particularly deep learning, can support image denoising, enhancement, resolution improvement, and three-dimensional localization, and may further assist in tumor recognition and grading, minimal residual disease assessment, and metastatic risk estimation. Overall, the integration of fluorescence imaging with AI is advancing oncology toward a more precise, intelligent, and integrated paradigm; however, key challenges remain, including probe biocompatibility and safety, clinical translation, and the lack of standardized imaging protocols.
- Funder
- National Natural Science and Foundation of China, Beijing Natural Science Foundation, Capital’s Funds for Health Improvement and Research, Shandong Provincial Natural Science Foundation