Control valve discovered in gut’s plumbing system
Peer-Reviewed Publication
Updates every hour. Last Updated: 4-May-2026 05:16 ET (4-May-2026 09:16 GMT/UTC)
Constipation and diarrhea are caused by how much fluid moves into the gut. Scientists studied a popular laxative to understand what controls fluid flow. Team found the laxative acts on an ion channel called TRPM4. Discovery reveals a new drug binding site that could enable more precise treatments for digestive disorders.
Using a tiny, acid-tolerant yeast, scientists have demonstrated a cost-effective way to make disposable diapers, microplastics, and acrylic paint more sustainable through biomanufacturing. Researchers at the University of Illinois Urbana-Champaign and Penn State University developed a bio-based method to produce 3-Hydroxypropanoic acid (3-HP), a precursor chemical for the acrylic acid used in those products, and validated its commercial potential for this lucrative market. The scientists are all part of the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI), a U.S. Department of Energy (DOE) Bioenergy Research Center.
The flagellar tails of bacteria rotate clockwise or counterclockwise because of active mechanical forces that pressure the individual ‘teeth’ of a gear to cooperate. This revises a decades-old model of how bacteria tails switch their rotational direction. The study, led by scientists at the Flatiron Institute, appears in Nature Physics.
Physicists from Trinity College Dublin believe new insights into the behaviour of light may offer a new means of solving one of science’s oldest challenges – how to turn heat into useful energy. Their theoretical leap forwards, which will now be tested in the lab, could influence the development of specialised devices that would ultimately increase the amount of energy we can capture from sunlight (and lamps and LEDs) and then repurpose to perform useful tasks.
Solid oxide fuel cells (SOFCs) offer a clean alternative to fossil fuel-based power generation, but their high operating temperatures hinder widespread use. In a recent study, researchers from Japan developed ultra-thin, highly ordered samarium-doped cerium oxide electrolyte films that overcome the long-standing issue of grain boundary resistance, enabling efficient operation at much lower temperatures. Their design achieved record-setting oxide-ion conductivity and paves the way for safer, more affordable SOFCs for sustainable power generation.
When the cell’s recycling stations, the lysosomes, start leaking, it can become dangerous. Toxic waste risks spreading and damaging the cell. Now, researchers at Umeå University have revealed the molecular sensors that detect tiny holes in lysosomal membranes so they can be quickly repaired – a process crucial for preventing inflammation, cell death, and diseases such as Alzheimer’s.