Pusan National University researchers develop light-activated tissue adhesive patch for rapid, watertight neurosurgical sealing
Peer-Reviewed Publication
Updates every hour. Last Updated: 9-May-2026 09:16 ET (9-May-2026 13:16 GMT/UTC)
Durotomy frequently results in cerebrospinal fluid leakage, leading to serious secondary complications. Tissue adhesives have become a popular alternative to sutures for achieving rapid, watertight sealing of dural tears. However, current materials cause excessive swelling and unwanted tissue adhesion. Now, researchers have developed an innovative monolithic Janus patch using a simple method that enables rapid sealing of dural tears through low-energy visible-light activation, while exhibiting minimal swelling (reduced mass effect) and excellent biocompatibility.
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