A new worm model developed by Brown University researchers could play a key role in treating a rare genetic disease that causes paralysis in children and worsens with age. Developed in the lab of neuroscientist Anne Hart, a genetically engineered C. elegans nematode model provides a fast, inexpensive way to evaluate potential drug treatments for alternating hemiplegia of childhood, or AHC, a disorder that currently has no cure or effective treatments.

Soils are home to some of the most diverse animal communities on Earth. These animals – including nematodes, springtails, mites, earthworms, spiders and other arthropods – drive decomposition, regulate microbial communities and contribute to nutrient cycling. However, little is known about how these animals’ “trophic diversity” – meaning the variety of feeding activities – is affected by land use and climate. An international research team led by the University of Göttingen has now shown that soil animal communities have greater trophic diversity in agricultural ecosystems and in tropical regions. The study analysed carbon and nitrogen stable isotope ratios from over 17,000 soil samples, covering 28 major groups of organisms from 456 sites across 19 countries. The results were published in Nature Ecology & Evolution.

For decades, scientists have known that estrogen protects cardiovascular health, but exactly how that protection works—and what happens when it disappears—has remained unclear. New research from University of Texas at Arlington points to the liver and the immune system as critical players.

A new study by University of Victoria and Pacific Salmon Foundation scientists has uncovered what adult Chinook salmon in the Salish Sea are eating—and revealed diet can differ according to region. 

Restoring dry forests in the Pacific Northwest, shaped by frequent low-intensity fire and widely spaced trees, often means thinning dense stands that accumulated after decades of fire suppression. This can make forests healthier and more resilient to wildfire, but it can raise concerns about protecting wildlife that depend on dense tree cover, including the northern spotted owl.

A new study by researchers at Oregon State University and the U.S. Forest Service and just published in Forest Ecology & Management, suggests that restoration of landscapes that historically burned frequently through planned, controlled fire does not have to conflict with spotted owl conservation.

Proteins change shape as they function, and these changes are essential for processes such as drug interactions and cellular activity. Researchers from the Tokyo University of Science developed an AI-based method called DeepAFM that is trained on millions of simulated images representing different protein states, accurately identifying transitions between closed and open states in a protein called SecA. This approach highlights the growing potential of AI to solve complex challenges in biology and medicine.

The function of transposable elements (TEs), during the conversion of stem cells into specialized cell types, remains poorly understood. A study shows that TEs act as binding platforms for key proteins involved in brain development, with many becoming active during neuronal differentiation. The study traces the evolutionary origins of these regulatory elements and demonstrates their role in gene regulation. These findings indicate that TEs may have expanded and refined gene regulatory networks in the brain.

- Achieving an international conservation target to protect almost a third of the world’s land and sea in the next four years could directly affect the lives of almost half the people on the planet, finds a new report.

- The study is the first to consider the social implications of the target at the global level.

- Supporting the people who live near areas that could be designated for nature - financially and otherwise - is vital for success.