Non-native diet makes Fischer’s Blue butterflies less attractive
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A new Thought Leaders invited review in Genomic Psychiatry synthesizes more than two decades of work on HuD, a neuronal RNA-binding protein encoded by the ELAVL4 gene. Drawing on RIP-seq and CLIP-seq data from embryonic and adult mouse brain, the authors compare close to 4,000 HuD-bound messenger RNAs and identify 1,926 shared targets. Despite different molecular casts at different ages, fifteen canonical pathways and thirty-one disease and function categories recur across development and maturity. The synthesis suggests that adult neuronal plasticity is, at the molecular level, a recapitulation of early development.A new Thought Leaders invited review in Genomic Psychiatry synthesizes more than two decades of work on HuD, a neuronal RNA-binding protein encoded by the ELAVL4 gene. Drawing on RIP-seq and CLIP-seq data from embryonic and adult mouse brain, the authors compare close to 4,000 HuD-bound messenger RNAs and identify 1,926 shared targets. Despite different molecular casts at different ages, fifteen canonical pathways and thirty-one disease and function categories recur across development and maturity. The synthesis suggests that adult neuronal plasticity is, at the molecular level, a recapitulation of early development.A new Thought Leaders invited review in Genomic Psychiatry synthesizes more than two decades of work on HuD, a neuronal RNA-binding protein encoded by the ELAVL4 gene. Drawing on RIP-seq and CLIP-seq data from embryonic and adult mouse brain, the authors compare close to 4,000 HuD-bound messenger RNAs and identify 1,926 shared targets. Despite different molecular casts at different ages, fifteen canonical pathways and thirty-one disease and function categories recur across development and maturity. The synthesis suggests that adult neuronal plasticity is, at the molecular level, a recapitulation of early development.
For the first time, scientists have directly measured how smoking changes the mechanical behavior of human lung tissue. The researchers found that smoking substantially stiffens this tissue in ways resembling fibrosis, a disease that scars and toughens the lungs.
For decades, ultrasound has been associated with diagnostics – a routine scan in a hospital room, a monitor displaying organs, tissues, or the first image of a baby. However, researchers are now looking at ultrasound from an entirely different perspective. New findings from scientists at Kaunas University of Technology (KTU) suggest that ultrasound waves might not only help doctors see inside the body, but low-frequency ultrasound directly influences blood flow – potentially opening new possibilities to support the treatment of cardiovascular diseases, Alzheimer’s disease, and diabetes, reducing the need for invasive procedures or medication in the future.
Davis Joseph was awarded the 2025 Ciechanover International Biology Award at the Sustainability through Science and Technology Summit 2025 (FLOGEN SIPS 2025) in Cebu, Philippines, for a breakthrough cancer discovery proposing organ-agnostic treatment strategies. His work identifies three universal cancer types based on dysfunctions in p14ARF/p53, DINO lncRNA, and MDM2 activity, and introduces a universal apoptosis network flowsheet built from the analysis of 174 scientific publications. The discovery supports a unified therapeutic framework for treating cancers regardless of the organ in which they originate and is presented as an example of Sustainable Medicine under the FLOGEN Sustainability Framework.
A new independent report has found that EMBL-EBI data resources are a critical global infrastructure for the life sciences, delivering multi-billion-pound value every year.
A new study published in the journal Environmental Conservation finds almost three-quarters of Brazil’s federal nature reserves lack adequate funding, with nearly all Amazon parks facing major financial shortfalls.