Rare gain-of-function variant in BMPR2 identified as new cause of neurodevelopmental disorders
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Oct-2026 14:16 ET (22-Oct-2026 18:16 GMT/UTC)
Cysteine is the only protein-building amino acid that is acutely toxic to human cells when present in excess. Cells avoid this toxicity by converting cysteine into glutathione. Scientists had long puzzled over why excess cysteine is dangerous, while a large amount of glutathione is safe. A new study shows that excess cysteine causes the release of iron, which accumulates inside mitochondria and ultimately triggers cell death. Glutathione gives the cell many of the same advantages as free cysteine, without unleashing unsafe levels of iron. Beyond clarifying fundamental mysteries underlying the basic biology of human cells, the findings may also have implications for cancers that take up large amounts of cysteine.
Insect ‘detectives’ have discovered two new types of large stick insects, showing scientists are still uncovering new species in some of Australia’s most well-studied landscapes.
Cell division, a process fundamental to life, still holds surprises. Researchers from the University of Zurich and the Spanish National Cancer Research Centre (CNIO) have discovered a key mechanism that allows cells to protect genetic information as they divide.
The discovery centres on cohesin, a key protein involved in genome folding inside the cell nucleus.
Understanding this basic cellular process could have implications for precision oncology, as many cancer therapies work by triggering the very errors that this mechanism prevents.
Cambridge scientists have shown that girls and boys show differences in what they pay attention to, even at birth. Since these differences are present so early, it is possible they emerge due to prenatal factors. The findings suggest that some psychological differences between males and females (such the development of social skills) may be influenced by both prenatal biology as well as later experience.