Small-molecule–mediated precision protein editing in living cells
Peer-Reviewed Publication
Updates every hour. Last Updated: 16-Jun-2026 22:16 ET (17-Jun-2026 02:16 GMT/UTC)
Researchers develop light-induced Asp(D)-to-Ala(A) protein editors (LIDAPEs) which enable site-specific residue editing of endogenous protein in living cells, and lay the foundation for a new class of chemical biology tools.
Harbour porpoises were once found across a much wider area of the Baltic Sea than they are today, including regions where they are now rare or absent. This is shown in a new study that uses centuries-old Swedish newspapers to reconstruct past distribution patterns.
Biologists have long puzzled over why organisms with similar numbers of protein-coding genes can differ so dramatically in nervous system complexity. New research points to a potential link between the expanding diversity of RNA-binding proteins, which shape how genetic instructions are processed, and greater brain sophistication.
Researchers develop an interpretable hybrid feature selection model to overcome the "curse of dimensionality"in genomic selection, pinpointing key genetic markers for global food security.
Konstanz molecular biologist Elke Deuerling has been admitted to the German National Academy of Sciences, the "Leopoldina". By selecting Elke Deuerling as a member, the Academy recognizes her outstanding contributions to the field of life sciences, particularly to proteostasis research.
Researchers have discovered a “control switch” inside our immune cells that helps the body destroy dangerous fungal infections.
The team found that a protein called RAB5c helps white blood cells kill Aspergillus fumigatus – a common airborne fungus that can cause life‑threatening lung infections in people with weakened immune systems.
The study reveals that without this protein, immune cells are effectively disarmed – even though they appear to be attacking at full force.
The findings could have major implications for treating fungal infections – which are notoriously hard to diagnose and often resistant to drugs.
The team hope their breakthrough could lead to new treatments for vulnerable patients.