Inhibitory neurons catch up during brain development
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Updates every hour. Last Updated: 20-Oct-2025 23:11 ET (21-Oct-2025 03:11 GMT/UTC)
A fundamental discovery by University of Missouri scientists could help solve one of the most frustrating challenges in treating lung cancer: Why do some patients initially respond to drug treatment, only for it to stop working 18 months later?
The team, led by Dhananjay Suresh, Anandhi Upendran and Raghuraman Kannan at Mizzou’s School of Medicine, identified a hidden molecular “seesaw” involving two proteins inside cancer cells — AXL and FN14. When investigators try to block one protein to stop the cancer, the other one takes over, helping the tumor survive. To fix this, the team developed a new solution: a gelatin-based nanoparticle that can shut down both proteins at the same time.
Recently, Hangzhou Institute of Medicine (HIM), University of Chinese Academy of Sciences (UCAS), Guangzhou National Laboratory and other research institutes published a perspective entitled Redefining imaging genomics for the next decade on Science Bulletin, in which the article systematically summarizes the existing advancements in imaging genomics, and proposes a framework for imaging genomics that provide a new path for precision medicine.
Predatory fish that evolved into the first terrestrial animals on Earth are still revealing insights into the origins of mammals – including new research into the eating habits of lobe-finned fish which inhabited an ancient reef in northern Australia.
In new research in iScience journal, an international study led by Flinders University reveals new insights into the lives of 380-million-year-old lungfish after a high-tech examination of ‘remarkable’ well-preserved jawbones found in the remote Gogo fossil field in northern Western Australia.