An invisible intruder puts the delicate balance in our lungs to the test: the mold Aspergillus fumigatus, harmless in nature, can become a serious danger if the immune system is weakened - and change the entire bacterial world in the lungs. But that's not all: the intestines and metabolism also appear to be affected by a lung infection.

The rapid evolution of SARS-CoV-2 variants during the COVID-19 pandemic emphasized the need for advanced tools to predict future outbreaks. The study introduces CoVFit, an AI-driven model that analyzes spike protein mutations to assess the fitness of SARS-CoV-2 variants. By combining molecular and epidemiological data, CoVFit provides early insights into the transmissibility and immunity evasion of emerging variants, offering a powerful tool for pandemic preparedness, vaccine design, and global risk assessment.

Most plants form symbioses with mycorrhizal fungi since their emergence on land hundreds of millions of years ago. Depending on the availability of carbon (C), these symbioses employ two nutrient acquisition strategies: (i) via mycorrhizal fungi and (ii) via roots. While nutrient acquisition through symbiotic ectomycorrhizal fungi is C costly, it is fundamental for plant growth, community and ecosystem functioning.

Researchers used high-throughput DNA sequencing to measure biodiversity along a transect – a succession from recently exposed to mature soil – in front of a glacier in Antarctica. To capture a detailed ecological ‘time sequence’ they distinguished between intracellular and extracellular DNA from living versus dead or locally extinct species. They found an abundance of previously unsuspected interactions between eukaryotes and prokaryotes, eg, algae with heterotrophic bacteria and fungi with actinobacteria. The results imply that novel mutualistic interactions play an essential role in shaping this system, and that biodiversity in Antarctica may be much greater than previously thought.