Gram, Denmark — An associated set of gigantic vertebrae belonging to the iconic extinct Megalodon or megatooth shark that had been missing in action since the 1980s was discovered, providing new information about the shark’s lifestyle. Two Museum of Southern Jutland staff, Mette Elstrup and Trine Sørensen, and a researcher at Aarhus University, Henrik Lauridsen, teamed up with a scientist in the United States and another in Australia and took a renewed look at a once-lost vertebral specimen of Otodus megalodon, the fossil shark that lived nearly worldwide about 15 to 3.6 million years ago.  The new study appears in the international journal Palaeontologia Electronica.

Perivascular adipose tissue (PVAT), the fat layer surrounding blood vessels, is increasingly recognized as an active regulator of vascular function rather than a passive structural cushion. Yet whether PVAT contains functionally important sympathetic nerves has remained debated, largely because conventional two-dimensional imaging can miss sparse, spatially complex neural structures.

A new study led by the University of Plymouth has used more than six decades of data to show that plankton abundance is declining across vast swathes of the North East Atlantic – a region covering the Atlantic Ocean from Portugal to Norway, and the entirety of the North Sea.

This clinical case report highlights that generalized skin hyperpigmentation, particularly at friction and pressure sites, may be the initial and most prominent sign of Addison’s disease (primary adrenal insufficiency). Early recognition of this dermatological manifestation enables timely diagnosis and life-saving treatment, preventing potentially fatal adrenal crisis.

A retrospective ultrasound study of 76 psoriasis patients shows that six weeks of secukinumab treatment significantly reduces subclinical enthesitis—early inflammation at tendon attachment sites—suggesting early IL-17A blockade may help prevent progression to psoriatic arthritis, a disabling complication affecting up to 5.8% of Chinese psoriasis patients.

Researchers clarify a long-standing diagnostic confusion by distinguishing two distinct steroid-induced facial skin conditions: steroid-induced rosacea (SIR) and steroid-induced rosacea-like dermatitis (SIRD). This new classification provides clear clinical guidance, prevents ineffective or harmful treatments, and improves outcomes for millions of patients affected by topical steroid side effects.