Low-viscosity oil boosts PDMS SlipChip: Enabling safer cell studies and gradient generation
Peer-Reviewed Publication
Updates every hour. Last Updated: 4-Nov-2025 09:11 ET (4-Nov-2025 14:11 GMT/UTC)
Researchers at Toyohashi University of Technology in Japan, in collaboration with the Institute of Translational Medicine and Biomedical Engineering (IMTIB) in Argentina and the Indian Institute of Technology Madras, have advanced the "PDMS SlipChip," a versatile microfluidic device. By using a low-viscosity silicone oil and fine-tuning the fabrication process, they've made the SlipChip more reliable for cell-based experiments and simpler for creating concentration gradients. This breakthrough tackles previous issues like channel clogging and potential harm to cells, opening new avenues for biomedical research, including drug development and sophisticated cell studies.
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