Peking University, February 1, 2026: A research team led by Prof. Lei Xiaoguang(http://www.chem.pku.edu.cn/leigroup/) at Peking University has achieved a major scientific breakthrough in the field of biosynthesis and biocatalysis. For the first time, they have developed a novel biocatalytic strategy that differs fundamentally from existing methods in terms of mechanism and synthetic logic, enabling transformative synthesis of amide bonds. This seminal discovery was published in Science on January 29, 2026, under the title: "Engineered aldehyde dehydrogenases for amide bond formation."