Chemolithoautotrophic breakthrough: bacteria converts CO2 into p-coumaric acid without light
Peer-Reviewed Publication
Updates every hour. Last Updated: 30-Oct-2026 10:16 ET (30-Oct-2026 14:16 GMT/UTC)
In a significant advance for carbon-negative biotechnology, researchers have engineered the chemolithoautotrophic bacterium Cupriavidus necator H16 to convert carbon dioxide (CO2) directly into p-coumaric acid (p-CA), a high-value phenolic compound. Published in Systems Microbiology and Biomanufacturing, this study marks the first demonstration of light-independent, de novo synthesis of p-CA from CO2, presenting a sustainable alternative to traditional plant extraction and petrochemical synthesis methods.
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