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Updates every hour. Last Updated: 25-Oct-2026 15:15 ET (25-Oct-2026 19:15 GMT/UTC)
Why This Research Was Needed
Ankle fractures are becoming more common among older adults, and surgery to fix them carries a complication rate of up to 30%. One of the most serious complications is a fracture-related infection (FRI) — an infection that develops at or around the fracture site following surgery — which almost always requires a second operation. Despite this, little was known about which patients are most at risk, especially those aged 50 and older. A research team led by Dr. Molham Najjar, from the Department of Orthopaedics and Traumatology at University Hospital Basel, University of Basel, Switzerland, and the Department of Orthopaedics and Trauma Surgery at Hirslanden Klinik Birshof, Basel, Switzerland, set out to change that.New research published in Gastroenterology highlights how culture, social environment, stress, and economic conditions influence disorders of gut–brain interaction, including irritable bowel syndrome. The review, co-authored by Professor Agata Mulak of Wroclaw Medical University as part of the Rome V Criteria update, argues that sociocultural factors play a significant role in symptom development, healthcare-seeking behavior, and treatment outcomes. The findings support a more holistic and personalized approach to gastrointestinal care.
Europe’s food system is under growing strain from climate change, environmental pressures, and rising levels of diet-related disease. Although the EU has set ambitious goals for a greener, healthier, and more competitive and resilient agrifood system, progress remains slow. A new perspective published in Nature Food examines this gap between ambition and reality and identifies the structural barriers holding transformations back.
The study is the first output of a new European research alliance, bringing together researchers from, among others, Aarhus University in Denmark, Wageningen University & Research in the Netherlands and the French National Research Institute for Agriculture, Food and Environment (INRAE). Drawing on contributions from 34 researchers, it takes a system-wide perspective on the agrifood system, from production to consumption.
The researchers argue that the challenge is not only a lack of knowledge or willingness to change. Many actors across the food system, like farmers, policymakers, and consumers support reform. However, they operate within “lock-ins”: self-reinforcing systems of incentives, regulations, market structures, and habits that sustain the status quo.
Five key lock-ins are highlighted. First, fragmented policymaking leads to conflicting objectives across agriculture, health, environment, and trade. Second, dietary habits are difficult to shift, as cultural norms, prices, and availability often favor less sustainable food choices. Third, market structures emphasize efficiency, scale, and low costs, discouraging long-term investments in sustainability. Fourth, environmental costs such as emissions and biodiversity loss are not reflected in food prices, limiting the competitiveness of sustainable alternatives. Finally, increasing instability from climate change to geopolitical shocks exposes the fragility of a system optimized for efficiency rather than resilience.
Importantly, the authors propose five guiding principles for change in the agrifood system: prioritizing access to affordable, healthy and sustainable food; ensuring inclusive and engaging transformation processes; provide governance to strengthen transparency and accountability; leveraging Europe’s diversity in agrifood systems; and shifting mindsets towards prioritizing common goods.
The researchers emphasize that transformation will require more than technological solutions. Coordinated policy action, new incentives, and strong leadership are essential to unlock systemic change and move Europe’s food system forward.
Today's children are absorbing screens at scales no previous generation has known, during the precise developmental windows when neural architecture is most malleable. A new Thought Leaders Invited Review in Brain Health offers a framework for understanding what that means. Michel Cuenod, Julio Licinio, and Kim Q. Do introduce the criticome: the complete ensemble of sensory, motor, social, cultural, and environmental experience integrated by the brain during critical periods from before birth through roughly age twenty-five. The synthesis grounds the term in six neurobiological mechanisms and reframes autism, schizophrenia, post-traumatic stress, and major depression as developmental rather than purely synaptic disorders.