New study maps four key pathways to Alzheimer’s disease
Peer-Reviewed Publication
Updates every hour. Last Updated: 23-Dec-2025 16:11 ET (23-Dec-2025 21:11 GMT/UTC)
UCLA Health researchers have identified four distinct pathways that lead to Alzheimer's disease by analyzing electronic health records, offering new insights into how the condition develops over time rather than from isolated risk factors.
A new study conducted at Reichman University’s School of Sustainability presents an innovative tool to help decision-makers better understand the condition of streams and thereby advance their restoration and rehabilitation. The tool, called SESBI — the Stream Ecosystem Services and Biodiversity Index — is designed to measure what is called “stream health,” meaning the degree to which a stream functions ecologically and contributes to public welfare.
Researchers from the Josep Carreras Leukaemia Research Institute and the Aragon Health Research Institute have just presented a new strategy in the fight against T-cell Acute Lymphoblastic Leukaemia. This novel therapy is based on the use of CAR-T cells designed to target two specific markers of this type of leukaemia: the CD1a and CCR9 proteins. Preclinical results of this new therapeutic approach demonstrate both high efficacy and an excellent safety profile, paving the way for clinical development in the short term.
Patients with glioblastoma (GBM)—a type of brain cancer—have a poor prognosis owing to the aggressive nature of GBM disease and limited GBM treatment options. A new study by researchers from Croatia provides critical insights into the transformative role of artificial intelligence (AI) in advancing the diagnosis and treatment of GBM. From accurately distinguishing tumor tissue in GBM to enabling personalized treatment, AI-based tools and models can revolutionize GBM treatment and care.
Our metabolic processes differ depending on the time of day and many of them are more active in the morning than in the evening. Although studies show that eating late in the day is associated with an increased risk of obesity and cardiovascular diseases, little is known about how the time when we eat affects glucose metabolism and to what extent this is genetically defined. Prof. Olga Ramich from the German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE) and her team recently investigated this in a twin cohort. The article was published in the journal “eBioMedicine.”
Metabolism follows the internal clock