According to international studies, taking Acetylsalicylic acid daily can protect people with Lynch syndrome from developing colorectal cancer – even at low doses. Researchers from the University Hospital Bonn (UKB), the University of Bonn, and the Center for Integrated Oncology (CIO) Bonn, in collaboration with the self-help organization SemiColon, have now found that these scientific findings have so far been insufficiently incorporated into clinical practice. The results of the LYNX study have now been published as a letter in the journal *The Lancet Gastroenterology & Hepatology*.

Climate policy models usually assume people hold accurate beliefs about climate damages. A new study builds disinformation into a climate–economy model and finds that informed democratic majorities can deliver stronger carbon taxes than a politically constrained planner, but this advantage collapses abruptly once disinformation tips the majority. Late and persistent disinformation yields the most severe warming, while counter-disinformation efforts can largely restore effective policy.

A perspective published in the Journal of Bioresources and Bioproducts examines the emerging role of silk fibroin (SF)/polylactic acid (PLA) composite scaffolds in bone and related tissue regeneration. The review brings together evidence on material chemistry, scaffold architecture, interfacial bonding, degradation, mechanotransduction, osteogenesis, angiogenesis and immunomodulation. Rather than treating fabrication methods or biological responses separately, the authors discuss how these factors interact to determine scaffold performance. The review also assesses evidence across in vitro, animal and translational studies, concluding that substantial work remains before SF/PLA scaffolds can move toward human clinical applications.

Vaccination not only prevents disease caused by acute infection but also protects against long-term immune-related sequelae that can follow an acute viral infection. This is the main conclusion of a study led by the Infection Biology Laboratory at Pompeu Fabra University. The study, carried out in mice, shows how after recovering from an acute viral infection, animals experienced a long period of impaired immune responsiveness which compromised their immune system's ability to effectively respond to future challenges. Prior vaccination prevented these detrimental consequences, preserving immune function, thus broadening our understanding of the benefits of vaccination.