Pelvic organ prolapse (POP) affects millions of women, causing pain and diminished quality of life. Current options are limited, with surgery often the only choice. Lehigh University bioengineer Anand Ramamurthi, in collaboration with the Cleveland Clinic, has received NIH funding to develop a nonsurgical therapy using nanoparticles to regenerate pelvic tissue and slow or reverse POP progression.

BUFFALO, NY — August 27, 2025 — A new research paper was published in Volume 17, Issue 7 of Aging (Aging-US) on July 24, 2025, titled “RNA-binding protein AUF1 suppresses cellular senescence and glycolysis by targeting PDP2 and PGAM1 mRNAs.”