A breakthrough single-cell method for mapping DNA-protein interactions
Peer-Reviewed Publication
Updates every hour. Last Updated: 19-Jun-2026 04:15 ET (19-Jun-2026 08:15 GMT/UTC)
A new technology allows scientists to map, in single cells, the DNA binding sites of transcription factors and other regulatory proteins that control gene activity, according to a study led by investigators at Weill Cornell Medicine and the New York Genome Center. With key advantages over methods currently in use, the technology is expected to be a powerful addition to biologists’ toolkit for studying cells in health and disease.
Pulmonary Regurgitation (PR) is a common and significant complication after treatment of the congenital heart disease Tetralogy of Fallot. MRIs are the standard method to evaluate the severity of PR, but may not be accessible to all patients due to limited availability or contraindications such as pacemakers or claustrophobia. Researchers have developed a new technique using dynamic chest radiography to analyze PR severity that can evaluate it with 93% accuracy with only a seven-second scan.
To Joseph Sugerman, MD, a leading ear, nose and throat (ENT) specialist in Beverly Hills, human vocal cords are like finely tuned guitar strings or violins. They can be easily damaged by wear and tear and require the best of care to last a lifetime. For nearly 50 years, Dr. Sugerman has been providing patient-centered, personalized care to performers and non-performers alike, helping them preserve and restore their voices and prevent and treat hearing loss, as well as other conditions of the ear, nose and throat. Now, singer/songwriter Stevie Nicks—the first woman inducted twice into the Rock and Roll Hall of Fame—has made a major gift to establish the Stevie Nicks and Joseph Sugerman, MD, Endowed Chair in Otolaryngology at Keck School of Medicine of USC. Her contribution completed the $3 million goal for the endowed chair, which was also supported by generous gifts from other donors, all seeking to honor their longtime friend and caregiver. The inaugural holder of the Stevie Nicks and Joseph Sugerman, MD, Endowed Chair in Otolaryngology is Michael M. Johns, MD, director of the USC Voice Center, and a world-class expert in professional voice care. The idea to recognize Dr. Sugerman’s accomplishments by raising $3 million to establish an endowed chair came from Anita May Rosenstein and her husband, Arnold. Other patients quickly stepped forward to express their gratitude to their one-of-a-kind ENT physician. The giving cohort includes the Bloomfield Family Foundation, Barbara and Gary Brandt Family Foundation, James & Deborah Burrows Foundation, Crawford Family Foundation, Anne and Kirk Douglas Foundation, Lowell Milken Family Foundation, Arnold & Anita Rosenstein Family Foundation, The Fran and Ray Stark Foundation, and Howard Ruby.
Vitamin D levels remain low all year-round in key at-risk groups in England, challenging the belief that summer sunlight is enough to restore them.