Medicine & Health
Updates every hour. Last Updated: 26-Dec-2025 23:11 ET (27-Dec-2025 04:11 GMT/UTC)
HKUMed develops innovative organoid-based platform for precise evaluation of antibody and vaccine efficacy, accelerating FDA application of organoid technology
The University of Hong KongPeer-Reviewed Publication
- Journal
- Proceedings of the National Academy of Sciences
HKUMed develops world-first AI-powered fertilization-competent sperm identification tool: Over 96% accuracy boosts success rates in assisted reproduction
The University of Hong Kong- Journal
- Human Reproduction Open
Noisy knees not an early arthritis sign in young people, research shows
La Trobe UniversityPeer-Reviewed Publication
- Journal
- Arthritis Care & Research
HKUMed finds mislabelled penicillin allergy linked to serious joint infection risk after knee surgery; launches first pharmacist-led allergy service
The University of Hong Kong- Journal
- The Bone & Joint Journal
New method to study embryonic implantation offers hope for assisted reproduction
The University of OsakaPeer-Reviewed Publication
Researchers from The University of Osaka have found that they can keep mouse uterine tissue alive outside of the body, allowing them to directly observe embryonic implantation and development. Their technique brings hope for patients with infertility, and may allow for the development of therapies to treat recurrent implantation failure and improve the chance of implantation success using assisted reproductive technologies.Researchers from The University of Osaka have found that they can keep mouse uterine tissue alive outside of the body, allowing them to directly observe embryonic implantation and development. Their technique brings hope for patients with infertility, and may allow for the development of therapies to treat recurrent implantation failure and improve the chance of implantation success using assisted reproductive technologies.
- Journal
- Nature Communications
- Funder
- Japan Society for the Promotion of Science, Japan Agency for Medical Research and Development, Japan Science and Technology Agency, Astellas Foundation for Research on Metabolic Disorders, Naito Foundation, Children and Families Agency grant
Macrophages swallow damaged mitochondria through microautophagy
The University of OsakaPeer-Reviewed Publication
Researchers from The University of Osaka found that macrophages use microautophagy, mediated by Rab32-positive lysosome-related organelles, to directly engulf damaged mitochondria and other organelles. This was discovered to be independent of macroautophagy. Key factors in this process include Rab32 GTPase, PI(3,5)P2, ubiquitination, and p62/SQSTM1. By clearing mitochondria, microautophagy promotes metabolic reprogramming toward glycolysis, supporting M1 macrophage polarization. Loss of Rab32/38 disrupts this process, highlighting microautophagy’s role in regulating macrophage function.
- Journal
- Nature Communications
- Funder
- Japan Society for the Promotion of Science, Ministry of Education, Culture, Sports, Science and Technology