New meta analysis demonstrated that access to the GeneSight test can significantly improve response and remission rates for patients with depression. Compared to treatment as usual patients, those who were given the GeneSight test were 41% more likely to acheieve remission and 30% more likely to acheieve response. Results of the analysis have been published in the Journal of Clinical Pharmacology. 

Some sugar substitutes may come with unexpected consequences for long-term brain health, according to a study published in the September 3, 2025, issue of Neurology^®, the medical journal of the American Academy of Neurology. The study examined seven low- and no-calorie sweeteners and found that people who consumed the highest amounts experienced faster declines in thinking and memory skills compared to those who consumed the lowest amounts. The link was even stronger in people with diabetes. While the study showed a link between the use of some artificial sweeteners and cognitive decline, it did not prove that they were a cause.

Researchers from the Penn State College of Medicine uncovered a previously unknown role of the immune cell that are known for making antibodies. In response to flu infection, specialized B cells produce the key signaling messenger that is essential to developing robust, long-lasting immunity.

A large-scale cross-sectional study of older individuals in the UK supports contextual, process-based models of mental health that emphasise values-guided behaviour, psychosocial resources and biopsychosocial integration, according to a study published September 3, 2025, in the open-access journal PLOS Mental Health by Darren Edwards from Swansea University, UK, and colleagues. This has important implications for clinical and rehabilitation contexts, such that efforts to enhance well-being are complementary and have additional benefits over and above reducing distress.