Almost one billion people are projected to be living with osteoarthritis by 2050, up from about 600 million in 2023, and there remains no cure and no drug that can stop or slow the disease, according to a new roadmap published in The Lancet.

NUS Medicine-led review of more than 550,000 women finds earlier menopause and a higher number of births were associated with modestly greater biological age acceleration, offering new insights into women’s health and healthy longevity

Institutional fear of litigation, reputation damage and career consequences can create a protective shield around the small minority of doctors who commit serious crimes against patients, experts warn.

Recent research has suggested that folic acid (vitamin B9) supplementation may reduce the risk of suicide attempts. However, a nationwide Swedish study, presented at European College of Neuropsychopharmacology (ECNP) annual congress, indicates doubts over the benefits to supplementation, as folic acid appears to affect different sexes and age groups differently.

A pilot study suggests that low doses of LSD may have different effects on sustained attention in women and men, adding to growing evidence that people may not all respond to psychedelic microdosing in the same way.

A modeling analysis of health data for 20 countries found that among preventive healthcare services, increasing control of high blood pressure may save the most lives, more than 518,000 fewer deaths particularly in upper and lower-middle-income countries. 

A longitudinal metabolomics study of 28 patients with house dust mite-induced allergic rhinitis and 19 healthy controls found that plasma and nasal secretions capture distinct but complementary aspects of disease biology. After six months of clinically effective subcutaneous immunotherapy, both compartments shifted toward healthy profiles, but nasal metabolic recovery was more evident, revealing coordinated yet asynchronous systemic-local remodeling.

The health of the next generation will be shaped not by one defining crisis, but by a set of 17 interlinked catastrophic threats spanning disease, social and economic conditions, environmental change, technology and conflict, finds a new Commission published in The Lancet and launched at the World Health Summit 2026 in Berlin. For the first time, it provides decision-makers with a common framework to understand these threats and target action.