RNA viruses' rapid evolution challenges conventional diagnostics like reverse transcription quantitative polymerase chain reaction, as mutations can cause detection failures. Researchers from the Shenzhen Institute of Advanced Technology prospected a dual-strategy for RNA virus detection in Medicine Plus: mutation-tolerant broad screening and precise variant discrimination. Integrating these into portable, multiplex devices using real-time genomic data is key for effective public health responses.

Researchers led by the University of Vienna and Liège University Hospital Centre have identified genetic variants associated with a rare inherited growth disorder in two prehistoric individuals who lived more than 12,000 years ago. Using ancient DNA analysis and modern clinical genetics, they diagnosed the condition in a mother and daughter buried together in southern Italy. Published in the New England Journal of Medicine, the study shows that paleogenomics can now reconstruct ancient population history and diagnose rare genetic diseases in prehistoric individuals.

A new nanocomposite material made of carbon fiber-reinforced polymers and piezoelectric materials can use vibrations to self-detect tiny cracks. This material could be used in the aerospace, automative, and construction industries to monitor structural health without the need of an external power source.