Anxiety and depression are major global mental health challenges. Current treatments offer relief but remain unsatisfactory. New research reveals how stress, brain circuits, and genes interact, pointing to better diagnosis and personalized therapies. A recent review in the journal Science China-Life Sciences, led by Chinese researchers, highlights advances from neurobiology, genetics, and psychosocial studies to guide more precise and individualized treatments.

Using nanoparticles shaped like bottlebrushes, MIT chemists can deliver a large range of chemotherapy drugs directly to tumor cells, which could reduce the side effects of treatment.

New AI tool accurately identifies multiple drivers of disease in cells and predicts therapies that can restore cells to healthy function.

The advance moves away from traditional drug discovery approaches that look for and target single sources of cell dysfunction and instead aims to address underlying disease processes.

The new AI model sets the stage for better drug discovery and could lead to better individualized therapies.

The International Osteoporosis Foundation (IOF) has issued a landmark Position Paper identifying critical global barriers to osteoporosis care and calling for urgent change to improve access to effective fracture prevention strategies. Endorsed by more than 85 national and global organizations in the field, the paper identifies a number of key obstacles, including limited availability of bone density (DXA) scanning, outdated treatment criteria that rely solely on bone mineral density (BMD), and confusion surrounding diagnostic versus intervention thresholds. It urges a paradigm shift in how bone health in older age, including osteoporosis, is managed worldwide. 

Implementing changes to indoor environments, such as cooler bedrooms at night and increasing the amount of bright light during the day, could significantly improve sleep for people living with dementia, according to a study led by the University of Surrey.