About The Study: This decision analytical model study estimates that COVID-19 vaccination (primarily annual COVID-19 vaccination) during pregnancy will likely continue to yield meaningful public health benefits in the U.S., especially to reduce COVID-19 hospitalizations in infants. COVID-19 vaccination during pregnancy has been shown to be safe. While there is global variation in policy recommending COVID-19 vaccination during pregnancy, the U.S. has a high risk of severe COVID-19 in newborns, underscoring relevance of maternal COVID-19 vaccination.