Results from two studies find new implant restores blood pressure balance after spinal cord injury. In a rare double publication in both Nature and Nature Medicine, a pair of landmark studies by Dr. Aaron Phillips, PhD, UCalgary, Dr. Grégoire Courtine, PhD, EPFL, and Dr. Jocelyne Bloch, MD, UNIL, describe the development of a targeted therapy to address blood pressure regulation in 14 participants across four clinical studies conducted at three separate medical centers in Canada, Switzerland, and the Netherlands. The implantable neurostimulation system evaluated in these studies was developed by ONWARD Medical. The company recently received FDA approval to initiate a pivotal trial of this therapy, which is expected to involve approximately 20 leading neurorehabilitation and neurosurgical research centers across Canada, Europe and the United States.

Two healthcare workers get COVID-19 vaccinations on the same day. Both show strong antibody responses initially, but six months later one stays healthy while the other contracts the virus. A new study published in Science Translational Medicine could help explain this difference. Researchers tracked individuals’ antibody levels after vaccinations and identified four distinct patterns of immune response after the first booster vaccination. Notably, the group that started with the highest antibody levels but experienced a faster decline were infected earlier. People with lower blood levels of IgA(S) antibodies, which protect the nose and throat, were also at higher risk. The findings suggest that monitoring how antibody levels change over time could assist in identifying individuals at greater risk of infection.