Women are more likely to survive cancer than men but face a higher risk of serious and adverse side effects from treatment, according to a landmark international study from Adelaide University.

Published in the Journal of the National Cancer Institute (JNCI) and conducted in partnership with a international collaborators, the research identified consistent differences between male and female cancer patients in both survival and treatment toxicity.

Female patients had a 21% lower risk of death compared with male patients, yet a 12% higher risk of severe toxicities.

A multinational research team led by Shanghai University has published a comprehensive review detailing the biological characteristics of extracellular vesicles (EVs), their interaction mechanisms with the cardiovascular system, and cutting-edge bioengineering strategies to enhance EV functionality. The review highlights that bioengineered EVs, with optimized targeting and cargo delivery capabilities, show great clinical potential in protecting the myocardium, regulating vascular homeostasis and promoting cardiac regeneration, opening a new era for precision therapy of cardiovascular diseases such as myocardial infarction and heart failure.

A groundbreaking study unveils how coronaviruses, including SARS-CoV-2, hijack a host protein called HGS to create large, specialized "vesicles" that act as efficient virus assembly factories during late infection. Using advanced imaging, the team visually confirmed viruses being built inside these structures. Disabling HGS drastically reduced virus production, identifying it as a promising new target for broad-spectrum antiviral drugs.

Prostate cancer screening compares favourably to screening for breast cancer in identifying significant cancers, reducing mortality and avoiding unnecessary harms, says new research.