Social disadvantage can accelerate ageing and increase disease risk
Peer-Reviewed Publication
Updates every hour. Last Updated: 13-May-2025 08:09 ET (13-May-2025 12:09 GMT/UTC)
People with favourable socioeconomic conditions, such as high incomes or education levels, face a reduced risk of age-related diseases and show fewer signs of biological ageing than peers of the same age, finds a new study led by University College London (UCL) researchers.
Antimicrobial resistance has recently increased due to emerging carbapenem-resistant Klebsiella pneumoniae and extended-spectrum β-lactamase (ESBL)-producing strains of K. pneumoniae. Osaka Metropolitan University researchers conducted a systematic review and meta-analysis to evaluate the prevalence of ESBL-producing and carbapenem-resistant strains in hmKp and non-hmKp clinical isolates.
USC researchers have found that proteins and pathways involved in inflammation are associated with changes in bone mineral density (BMD) over time. The research, could potentially lead to the identification of biomarkers that would serve as early indicators of a person’s risk for bone health issues later in life. The study followed 304 obese/overweight Latino adolescents between the ages of 8 to 13 at baseline from the Study of Latino Adolescents at Risk for Type 2 Diabetes over an average period of three years. The researchers examined associations between over 650 proteins and annual measures of BMD. The proteins found to be associated with BMD were then inputted into a protein pathway database, which showed that many of the proteins associated with BMD were involved in inflammatory and immune pathways in adolescent populations. Researchers also examined associations between BMD and a subset of protein markers from the initial proteins, in a separate cohort of young adults. The research showed that several proteins had similar associations with lower BMD.
Researchers from Brazilian, Argentine, and Uruguayan institutions analyze the barriers that low- and middle-income countries face in disseminating research on intensive care medicine, particularly in the treatment of critically ill patients. Published this month in The Lancet, the study highlights how historical and economic biases perpetuate inequalities and suggests changes to make the scientific publishing system more inclusive and representative of the global community.
Polycystic kidney disease (PKD), a family of genetic disorders that causes clusters of cysts to form on the kidney, is among the most common genetic disorders, affecting some 500,000 people in the United States. Roughly one in every 1,000 people will develop some form of cystic kidney disease during their lifetime, and nearly 40,000 Oklahomans have a chronic kidney disease, according to the Oklahoma Health Care Authority.