RNA-based gene therapy may enable effective treatment for ALS – a fatal incurable neurodegenerative disease
Peer-Reviewed Publication
Updates every hour. Last Updated: 14-Jan-2026 10:11 ET (14-Jan-2026 15:11 GMT/UTC)
Virtual reality (VR) use is often linked to reduced blinking, raising concerns about dry eye. This study examined the ocular surface during a 30-minute VR gaming session using a compact imaging system to observe the tear film in real time. Over the session, the tear film’s lipid-layer interference grade increased, indicating thickening of the lipid layer. Under these experimental conditions, this change may be associated with a lower likelihood of dry eye during VR use.
Pancreatic cancer is one of the deadliest types of tumors. A team at the Technical University of Munich (TUM) has discovered that pancreatic tumors exploit the body’s nervous system by forming so-called pseudosynapses. Through a specific receptor, the cancer cells take up the neurotransmitter glutamate, which drives tumor growth. The researchers now hope to identify drugs that can block this process in patients.
A newly developed mouse model enables real-time visualization of RNA Polymerase II (RNAP2) during DNA transcription, as reported by researchers from Science Tokyo. The team engineered mice to produce a fluorescent antibody that binds specifically to RNAP2 during active transcription. Their approach enabled super-resolution imaging of transcription sites in living cells, revealing differences in gene expression dynamics across cell types and developmental states.
Transposable elements play a significant role in regulating gene expression and genome architecture, influencing development, immunity, aging, and disease progression. A study from researchers in China reviews these elements' molecular mechanisms and clinical implications, highlighting their potential as biomarkers and therapeutic targets for conditions like cancer, neurodegenerative, and autoimmune diseases. This research opens pathways for personalized medicine by targeting disease-specific transposable element signatures.