2-Apr-2026
A new biomarker helps assess the aggressiveness of glioblastoma
Universitat Politècnica de ValènciaPeer-Reviewed Publication
Researchers from the Biomedical Data Science Laboratory (BDSLab) at the ITACA Institute of the Universitat Politècnica de València have developed a new method based on magnetic resonance imaging that enables objective quantification of the growth of the most aggressive brain tumours, particularly glioblastoma.
The study, published in the scientific journal Medical Physics, addresses one of the main clinical challenges in the diagnosis and treatment of this tumour: its high capacity to infiltrate healthy brain tissue.
In their work, the UPV's BDSLab team presents a new biomarker, the Dynamic Infiltration Rate (DIR), capable of identifying different patterns of tumour growth and independently predicting patient survival.
- Journal
- Medical Physics
- Funder
- MCIN/AEI/10.13039/501100011033, MICIU/AEI/10.13039/501100011033, SINUÉ (INNEST/2022/87 - Agència Valenciana de la Innovació, Spain, Programa INVESTIGO (INVEST/2022/298) and Grant CIAICO/2022/064 (Lalaby-Glio) funded by Generalitat Valenciana, Spain, Spanish Ministry of Science, Innovation and Universities (FPU23/02431), European Research Council (grants 758657-ImPRESS and 101213953-CHRONOS, Helse Sør-Øst Regional Health Authority (grants 2021057, 2017073, and 2023050), Research Council of Norway (grants 325971, 261984, 303249, 32543, and 356066, Norwegian Cancer Society (grant 309012 - SAFARI), Universitat Politècnica de València program of pre-doctoral contracts for doctoral training (PAID-01-24, Subprogram 1)