Metabolic dysfunction-associated steatotic liver disease (MASLD) is among the most common chronic liver diseases, and, when untreated, can progress to cancer, cardiovascular disease, and diabetes. Salk Institute scientists found that production of a protein called FGF1 in the liver varies throughout the day to affect fat release timing from the liver into the bloodstream, acting as a circadian pacemaker for liver fat metabolism. These findings illuminate a previously unknown circadian lipid trafficking mechanism in the liver, with implications for understanding how disrupted body clocks drive metabolic disease.

Researchers have created heart monitoring sensors that conform to the skin, are comfortable, and can be worn while people are moving. With performance comparable to sensors already on the market, the new technology can be made using existing manufacturing processes.

A University of Texas at Arlington researcher is leading a new study that investigates cardio-sarcopenia—the combined loss of heart and muscle health in aging adults.