Proteins with exposed arginine can selectively accumulate even on protein-resistant coatings, as reported by researchers from Science Tokyo. Through an in-depth analysis of which and how proteins adhere to various anti-fouling surfaces, the team found arginine disrupts the protective water layer that normally blocks adsorption. Their results will help scientists develop safer and more effective biocompatible materials for medical devices, such as stents and advanced biosensors.

Immunotherapy for gynecological tumors is in a period of rapid development, bringing new hope to patients but also facing some new problems. How to achieve better clinical translation and improve treatment strategies based on current experimental research requires our joint efforts.

Controlling Mpox may require more than a single intervention. Researchers from Hasanuddin University developed a mathematical model to examine how vaccination, treatment, quarantine, and educational campaigns could be combined to mitigate Mpox transmission. The full-control strategy reduced simulated infections by 97.85% compared with no intervention and was the most cost-effective among the strategies tested. These findings also underscore the importance of considering animal reservoirs to support long-term management of Mpox.

Targeted drug delivery directly to the liver has unlocked major breakthroughs across medicine, but constructing the chemical key to enter liver cells remains complex and costly. Researchers have now introduced a nature-inspired, mobile delivery platform utilizing polyrotaxanes—supramolecular thread-like polymers where ring-shaped cyclodextrin molecules can freely rotate and slide along a central axle chain, effectively bypassing traditional synthetic bottlenecks.

Ammonia is essential for fertilizers and is emerging as a zero‑carbon energy carrier, but its industrial production via the Haber‑Bosch process is energy‑intensive and emits large amounts of CO₂. Meanwhile, nitrate pollution from agriculture and industry has contaminated groundwater worldwide, threatening ecosystems and human health. Electrocatalytic nitrate reduction to ammonia (NO₃RR) offers an elegant solution: using renewable electricity to convert nitrate waste into valuable ammonia.

Astragalus polysaccharide reduces brain injury in mice and in human microbiota-transplanted models by restoring gut health, suppressing inflammation, and strengthening the intestinal barrier.