To improve adaptability of large language models to challenging tasks that require reasoning, MIT researchers found strategically applying a method known as test-time training with task-specific examples can boost the accuracy of an LLM more than sixfold.

About The Study: In this multicenter randomized clinical trial, a nontargeted screening approach was superior to targeted screening for identifying new hepatitis C virus infections among patients seen in 3 urban emergency departments. The substantial decrease in patients who went from diagnosis to sustained virologic response at 12 weeks highlights an urgent need for innovative models of hepatitis C virus treatment. 

About The Study: In this randomized clinical trial of antihypertensive chronotherapy, bedtime dosing provided better control of nocturnal blood pressure and improved the circadian rhythm, without reducing the efficacy on mean daytime or 24-hour blood pressure, or increasing the risk of nocturnal hypotension. These findings support the potential advantages of bedtime administration and offer new evidence to guide future research on antihypertensive chronotherapy. 

A sneeze. Ocean currents. Smoke. What do these have in common? They’re instances of turbulence: unpredictable, chaotic, uneven fluid flows of fluctuating velocity and pressure. Though ubiquitous in nature, these flows remain somewhat of a mystery, theoretically and computationally.