Researchers have re-determined the two-neutron separation energy S_2n (0.265–0.656 MeV) by employing the root-mean-square matter radius derived from experimental measurements as a key constraint. Utilizing the three-body Faddeev method, the team revealed a weakly bound system dominated by an s-wave configuration and identified signatures of Efimov-like excited states. This study offers deeper insight into exotic nuclear structure and provides valuable data support for the refinement of astrophysics and nuclear physics models.

On November 2, 2025, the research group led by Dr. Zeng Ling from Army Medical University systematically elucidated the molecular mechanisms, pathological processes, and latest clinical advances in sepsis-induced endothelial barrier dysfunction from the perspective of vascular endothelial cells. This work provides novel insights for precise intervention in sepsis and septic shock. The findings were published in Research under the title "Sepsis-Induced Endothelial Barrier Dysfunction: Mechanisms, Pathology, and Therapeutic Advances" (Research, 2025, Article ID: 0997, DOI: 10.34133/research.0997).

An international research team led by The University of Osaka has demonstrated that two-faced Janus nanoparticles can restore the effectiveness of antibiotics against drug-resistant bacteria. These particles disrupt the protective outer membrane of Gram-negative bacteria, which normally blocks antibiotics. This allows conventional drugs to regain access and kill the once-resistant microbes. This synergistic strategy restores the effectiveness of existing antibiotics, offering a new line of defense against the growing threat of superbugs and extending the utility of our current medical arsenal.

Liquid-liquid phase separation (LLPS) is a unique phenomenon that occurs during crystallization. In a new study, a group of researchers from Doshisha University, Japan, have investigated the non-equilibrium phase behavior of localized LLPS driven by initial solute concentration and antisolvent addition rate in a ternary water/ethanol/butylparaben system. The present findings provide insights that may help regulate LLPS in turn potentially paving the way for improved product quality in the pharmaceutical, agrochemical, and food industries.

The problem of antibiotic-resistant bacteria has many health experts worried. As disease-causing bacteria adapt to some of our ways to reduce them, especially with antibiotics, it presents an arms race which we appear to be losing. Researchers seek to improve the situation by looking at how bacteria adapt to antibiotics. For the first time, researchers including those from the University of Tokyo, through massive data analysis, discovered two different strategies bacterial plasmids may use to share their antimicrobial resistance with other bacteria. Computational analysis could help identify and forecast risks, and future lab experiments may aid researchers narrow down key areas for further investigation. 

A research team led by Prof. Dan Li at the Institute of Atmospheric Physics, Chinese Academy of Sciences, has developed the Regional Integrated Earth Model System version 4.0 (RIEMS4.0). The team's recent study published in the Journal of Geophysical Research: Atmospheres provides new, mechanistic insights into how regional air-sea coupling shapes the East Asian summer climate, representing a significant advancement in the realism of regional climate simulations.

The researchers revealed how nuclear clustering in the hypernucleus $_{\Lambda }^{21}Ne$ disappears as temperature increases, employing the finite-temperature Skyrme–Hartree–Fock method. This work provides broader insight into how thermal effects influence the structure and behavior of hot nuclear systems.

Professor Pan Xu's research group at Southeast University reported a photocatalytic hydrogen atom transfer (HAT) strategy, successfully achieving the deconjugated olefin isomerization reaction of α,β-dehydroamino acids. This resulted in the efficient synthesis of β,γ-dehydroamino acids, which are difficult to prepare using traditional methods, under mild conditions. The reaction uses decatungstate (TBADT) as a photocatalyst, selectively extracting the γ-C–H bond of the substrate under 390 nm illumination to form a delocalized allylic radical. Subsequently, through hydrogen atom transfer and tautomerism steps, the reaction drives the reverse thermodynamic double bond isomerization. This method exhibits good substrate applicability, excellent (E)-selectivity, and 100% atom economy, providing a new route for the synthesis of β,γ-dehydroamino acids and their derivatives, and showing significant application potential in medicinal chemistry and natural product modification. The article was published as an open access Research Article in CCS Chemistry, the flagship journal of the Chinese Chemical Society.