Researchers at Case Western Reserve University have developed an environmentally safer type of plastic that can be used for wearable electronics, sensors and other electrical applications.

Case Western Reserve University chemist Divita Mathur was awarded a National Science Foundation (NSF) Faculty Early Career Development Program (CAREER) grant for her research in synthetic DNA nanoparticles, which have potential applications in gene therapy.

Insilico team employed advanced molecular modeling techniques in combination with the company’s proprietary generative AI-based chemistry engine, Chemistry42, to efficiently design highly selective FGFR2/3 inhibitors featuring a novel core structure. This research, recently published in the Journal of Medicinal Chemistry, provides an innovative approach for the discovery and development of next-generation cancer therapies targeting FGFR2/3.

A new way to grow stem cells may help them release more of the signaling proteins they use to repair tissue, potentially improving future treatments.

Real-time monitoring of additive concentrations in acidic copper plating solution is critical for ensuring process stability and reliability in integrated circuit manufacturing. Traditional detection systems rely on bulky rotating platinum disk electrodes (2–3 mm diameter) that consume large solution volumes to maintain unrestricted flow at high speeds, complicating operational workflows and limiting miniaturization. A team of scientists has addressed these challenges by developing a novel electrochemical microfluidic workstation that combines 3D-printed microfluidic chips with static platinum ultra-microelectrodes. By integrating microfluidic programmed mixing, the system reduces single-test solution consumption to 220 microliters. Calibration curves based on additive effects on copper deposition kinetics enable concentration detection with average relative errors below 10%. Their work is published in the journal Industrial Chemistry & Materials on June 26.

Cell sheet preparation for use in tissue engineering and regenerative therapies could be significantly improved with the use of thermo-responsive polymer brushes, adjusted in length and density according to specific cell types