CU Cancer Center researchers identify the ‘switch’ that allows intestinal cells to regenerate after injury
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Updates every hour. Last Updated: 10-Sep-2025 11:11 ET (10-Sep-2025 15:11 GMT/UTC)
Researchers from the University of Colorado Cancer Center have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer.
Peter Dempsey, PhD, professor of pediatrics–developmental biology in the CU School of Medicine, and Justin Brumbaugh, PhD, assistant professor of molecular, cellular, and developmental biology at CU Boulder, recently published a paper in the journal Nature Cell Biology showing the importance of the H3K36 methylation process in regulating plasticity and regeneration in intestinal cells.
New research offers unprecedented insight into how an enigmatic enzyme, known as CDK7, drives the cell cycle and cell proliferation.
Peer review is the cornerstone of scientific publishing, ensuring that research is scrutinised by experts prior to publication, yet it can be notoriously slow. The journal, Biology Open, is taking a bold step to speed up the process with their Fast & Fair initiative. Recruiting paid reviewers in a proof-of-concept trial, the journal has provided first decisions about whether a paper is eligible for publication within seven business days on 20 manuscripts, revolutionising scientific publishing.
25 March 2025/Kiel. How is organic matter transported from productive coastal areas to the open ocean? Researchers from the GEOMAR Helmholtz Centre for Ocean Research Kiel and MARUM - Centre for Marine Environmental Sciences at the University of Bremen have now shown that eddies play a crucial role in this process. The swirling currents contain large amounts of energy-rich and essential fat molecules (essential lipids), which play a key role in marine food webs and the carbon cycle. The study has now been published in the journal Communications Earth and Environment.
A new study in Forest Ecosystems unveils innovative design strategies to dramatically improve Pinus tabuliformis, a cornerstone species of northern China's forests. The research focused on optimizing advanced generation breeding, revealing that direct selection significantly outperforms combined selection, delivering impressive gains: a 7.72% increase in diameter, a substantial 18.56% jump in height, and a remarkable 31.01% surge in overall volume. Furthermore, addressing the critical issue of inbreeding, the researchers developed the Improved Adaptive Genetic Programming Algorithm (IAPGA). This innovative strategy demonstrably reduces inbreeding by a significant 14.36% within advanced seed orchards established using the selected breeding population. The results are pivotal for sustainable forest management, promising enhanced ecological resilience and substantial economic benefits through increased timber yield and improved forest health. This study provides valuable insights for optimizing breeding programs and ensuring the long-term vitality of Pinus tabuliformis forests in China.