New hope in the fight against Hepatitis C: Broadly effective innovative vaccine design
Peer-Reviewed Publication
Updates every hour. Last Updated: 15-May-2025 06:10 ET (15-May-2025 10:10 GMT/UTC)
The development of an effective vaccine against the Hepatitis C virus (HCV) has posed a significant challenge for decades due to the high genetic diversity of the virus. A research team led by Prof. Dr. Thomas Krey from the Institute of Biochemistry and the Center for Structural and Cell Biology in Medicine at the University of Lübeck, in collaboration with international partners, has now achieved a major breakthrough: using so-called “epitope-focused immunogens,” they were able to induce broadly neutralizing antibodies (bnAbs) in laboratory models for the first time. The promising results of the study were published in the renowned journal Science Advances.
For the second consecutive year, three faculty members in the Department of Biology have received National Institutes of Health Maximizing Investigators’ Research Awards (MIRA) recognizing their sustained research potential in bacterial and applied phage biology, neurobiology, and behavioral and evolutionary biology.