Biology
Updates every hour. Last Updated: 19-Oct-2025 08:11 ET (19-Oct-2025 12:11 GMT/UTC)
Systematic investigation of tumor microenvironment and antitumor immunity with IOBR
FAR Publishing LimitedPeer-Reviewed Publication
The tumor microenvironment (TME) is a critical factor in antitumor immunity and treatment outcome in cancer therapy. We have developed an analysis tool called the immuno-oncology biological research (IOBR) to investigate the TME and its role in antitumor immunity. Leveraging multi-omics data, IOBR facilitates comprehensive analysis of TME characteristics, immune interactions, and their impact on immunotherapy outcomes.
- Funder
- National Natural Science Foundation of China, Guang Dong Basic and Applied Basic Research Foundation, Guangzhou Science and Technology Project
GLP-1 RA use and survival among older adults with cancer and type 2 diabetes
JAMA NetworkPeer-Reviewed Publication
- Journal
- JAMA Network Open
AI-powered biomarker system redefines thyroid cancer progression and subtypes
FAR Publishing LimitedPeer-Reviewed Publication
A new study introduces an AI-integrated dynamic biomarker system that detects early disease tipping points and classifies thyroid cancer into actionable subtypes, paving the way for precision diagnosis and treatment.
- Funder
- the 2020 Medical Science and Technology Research (Key) Program of Henan Province
Comprehensive multi-omics integration reveals B cell-derived ELL2 as a novel diagnostic and prognostic biomarker in sepsis
FAR Publishing LimitedPeer-Reviewed Publication
Through large-scale cohort analysis, researchers have established a novel and stable classification of sepsis patients. Multi-machine learning integrated prognostic models prove highly effective in identifying high-risk C3 subtype patients, offering significant clinical utility. ELL2 derived from B cells as a potential new biomarker for prognosis prediction and diagnostic differentiation in sepsis patients.
- Funder
- Natural Science Youth Foundation of Hebei Province
New R package revolutionizes gene set enrichment analysis visualization for biomedical research
FAR Publishing LimitedPeer-Reviewed Publication
Researchers at China Pharmaceutical University have developed GseaVis, a user-friendly R package that significantly enhances the visualization of Gene Set Enrichment Analysis (GSEA) results. This innovative tool addresses longstanding limitations in existing GSEA visualization methods, providing researchers with publication-ready, highly customizable plots that simplify the interpretation of complex genomic data.
- Funder
- National Key Research and Development Program of China, National Natural Science Foundation of China, Project Program of Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University
Stevia leaf extract has potential as anticancer treatment, researchers find
Hiroshima UniversityPeer-Reviewed Publication
When fermented with plant-derived bacteria, stevia leaf extract is toxic to pancreatic cancer cells but not to healthy kidney cells
- Journal
- International Journal of Molecular Sciences