A new study, published by a team of UBC Okanagan chemistry researchers, is creating a major rethink of how enzymes work. And how a quantum phenomenon helps an important enzyme control essential yet dangerous molecules.

Enzymes, also known as biocatalysts, are the tiny machines behind every process in living things, explains study co-author Hossein Khalilian, a doctoral student in the Irving K. Barber Faculty of Science’s Department of Chemistry. Enzymes make molecules that are crucial to life, while also breaking down molecules that are bad or unnecessary for us.

Aging skin stretches, contracts and buckles under pressure – and that’s how wrinkles form, according to new experimental evidence from scientists at Binghamton University, State University of New York. 

Researchers from Tufts University School of Dental Medicine have developed lab-grown skin that replicates the complexity of scleroderma. Made from patient-derived cells, the 3D tissue model increases understanding of how this and fibrotic diseases progress.

Colon cancer is often driven by cancer stem cells, which resist treatment and lead to relapse. In a recent study, researchers from Japan revealed how transcription factors CDX1 and CDX2 suppress cancer cell stemness by blocking β-catenin’s ability to activate key genes like LGR5. Their findings showed that CDX1/2 prevent the formation of key transcriptional complexes involving DSIF and PAF1, identifying these as critical regulators and potential therapeutic targets in colon cancer.