Sepsis and septic shock are the leading causes of death in intensive care units worldwide.  Controlling the dysregulated host response that drives inflammation, hemodynamic collapse, and multiple organ failure is challenging. In a comprehensive narrative review, Italian and French researchers examine the clinical applications of the oXiris® membrane, an advanced extracorporeal blood purification filter designed to combine continuous renal replacement therapy (CRRT) with targeted removal of inflammatory mediators and bacterial endotoxins in critically ill patients.

Researchers have demonstrated a new class of low-cost, scalable sensors that can be used to monitor electrical activity in human cerebral organoids. Because electrical signals are key to understanding brain function, this advance facilitates research into both neurodevelopment and genetic disorders such as Angelman syndrome.

Recent research shows that tumors in different organs host microbial communities capable of influencing cancer biology, immune responses, and the effectiveness of therapies, highlighting the need to standardize methods for studying intratumoral microbes.