American black bears sleep twice as much during hibernation periods as during summer months, spending just 1/3 of this time awake, per machine-learning analysis of data from captive bears recorded over a period of 5 years
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Updates every hour. Last Updated: 24-Oct-2026 19:16 ET (24-Oct-2026 23:16 GMT/UTC)
DepMap scientists have generated dependency data on nearly 150 three-dimensional cancer cell models across 10 cancer types.
The updated catalog reveals cancer phenotypes, cell states, and gene dependencies that are missed in traditional cell lines and shows that both model types are complementary because each captures biology that the other misses.
The integration of data on 2D and 3D models creates a more comprehensive DepMap, moving the resource towards its goal of capturing the complete landscape of cancer vulnerabilities.
A research project funded by NIH has generated one of the most extensive and diverse collections of patient-derived tumor models. Tumor tissue from hundreds of cancer patients contributed to the compendium of tumor models that will enhance the study of tumor biology and be an asset in accelerating the development of cancer therapies while guiding future research directions.