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Updates every hour. Last Updated: 26-May-2026 02:15 ET (26-May-2026 06:15 GMT/UTC)
Treatments for low back pain can cost thousands - but some of the best fixes are free
University of SydneyAmong the myriad medical treatments for low back pain – a leading cause of disability that affects more than 600 million people worldwide – new Australian research has found that simpler and relatively more affordable lifestyle solutions may make the biggest difference.
- Journal
- Arthritis Care & Research
- Funder
- National Health and Medical Research Council
Comparing four heat-inducible promoters in stably transformed sugarcane regarding spatial and temporal control of transgene expression reveals candidates to drive stem-preferred background/objective transgene expression
University of Illinois at Urbana-Champaign Institute for Sustainability, Energy, and EnvironmentInducible promoters provide remarkable utility when sustained transgene expression compromises plant development or agronomic performance. In this study, four different plant heat shock protein (HSP) promoters were characterized in the vegetative tissues of stably transformed sugarcane to evaluate their efficacy and spatial expression profiles when directing the expression of a uidA reporter gene. This study produced new quantitative knowledge on the temporal and spatial expression of HSP promoters in sugarcane, expanding the promoter toolbox for crop biotechnology to support gene function studies and biotechnology applications, including precision gene editing and complex metabolic engineering.
- Journal
- Frontiers in Plant Science
- Funder
- U.S. Department of Energy
How an ancient stem cell regulator shapes modern plant regeneration
Nanjing Agricultural University The Academy of SciencePlant regeneration relies on a delicate balance between stem cell renewal and differentiation, yet the evolutionary origin and functional limits of key regulators remain poorly understood.
- Journal
- Horticulture Research
AI is rewriting the rules of enzyme engineering—from faster prediction to smarter design
Nanjing Agricultural University The Academy of ScienceA research team maps the key tasks that define modern enzyme engineering—function annotation, structure modeling, and property prediction—and explain how AI methods now accelerate each step, from mining candidate enzymes in massive sequence databases to generating new variants with improved activity, stability, or selectivity.
- Journal
- BioDesign Research
From rare pigment to industrial bioproduct: How engineered microbes are boosting violacein production
Nanjing Agricultural University The Academy of Science- Journal
- BioDesign Research
Engineered probiotics emerge as programmable living medicines for complex diseases
Nanjing Agricultural University The Academy of Science- Journal
- BioDesign Research
Engineered RNA sensor detects and fights coronavirus inside living cells
Nanjing Agricultural University The Academy of Science- Journal
- BioDesign Research
Discovery, characterization, and application of chromosomal integration sites in the hyperthermophilic archaeon Sulfolobus islandicus
University of Illinois at Urbana-Champaign Institute for Sustainability, Energy, and EnvironmentSulfolobus islandicus, an archaeal model organism, offers unique advantages for metabolic engineering and synthetic biology applications owing to its ability to thrive under low pH and high temperature conditions. Although several genetic tools exist for this organism, the absence of well-defined chromosomal integration sites continues to limit its development as a cellular factory. A research team at the University of Illinois Urbana-Champaign employed the CRISPR-COPIES pipeline and a multi-omics strategy that integrates genomics and epigenomics to guide the selection of genomic regions suitable for integration. This work expands the genetic toolbox for non-conventional hosts, advancing the potential for robust platforms for synthetic biology and industrial biotechnology.
- Journal
- Trends in Biotechnology
- Funder
- U.S. Department of Energy, National Research Foundation of Korea, Gordon and Betty Moore Foundation