27-Sep-2024 Strategy to combat breast cancer involves two-pronged attack on enzyme that ‘feeds’ tumor Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication Promising results were obtained by a group at the Brazilian Center for Research on Energy and Materials (CNPEM), working with collaborators elsewhere. They combined inhibition of glutaminase, an enzyme that converts glutamine into nutrients for tumor cells, with inhibition of HuR, a protein that regulates the RNA of glutaminase. Journal Nature Communications Funder Fundação de Amparo à Pesquisa do Estado de São Paulo
26-Sep-2024 Presence of bacteria in soil makes flowers more attractive to pollinators, study shows Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication Experiments conducted at the Federal University of the ABC showed that nitrogen-fixing bacteria play a key role in the reproduction of a legume native to Brazil. Journal American Journal of Botany Funder Fundação de Amparo à Pesquisa do Estado de São Paulo
26-Sep-2024 New laboratory enhances agricultural resilience through partnerships in Tanzania The Alliance of Bioversity International and the International Center for Tropical Agriculture A cutting-edge laboratory in Arusha, Tanzania, co-managed by the Tanzanian Agricultural Research Institute (TARI) and the Alliance of Bioversity and CIAT, is set to provide research and service facility with access to advanced disease diagnostics, nutrition analysis and biotechnology research that are crucial for adapting to climate change.
25-Sep-2024 Brazil must reinforce protection of forests to meet climate change mitigation goals, study warns Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication In an article published in Perspectives in Ecology and Conservation, researchers affiliated with the National Space Research Institute (INPE) and the National Disaster Surveillance and Early Warning Center (CEMADEN) in Brazil discuss CO2 emission reduction challenges and solutions. Journal Perspectives in Ecology and Conservation Funder Fundação de Amparo à Pesquisa do Estado de São Paulo
23-Sep-2024 New study raises questions about validity of standard model of solar flares Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication Computer simulations based on the standard model did not account for observational data obtained via telescope, showing that other factors must be taken into consideration when analyzing the process. Journal Monthly Notices of the Royal Astronomical Society Funder Fundação de Amparo à Pesquisa do Estado de São Paulo
23-Sep-2024 Novel method detects biological oxidant derived from CO2 in cells Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication A study conducted at the University of São Paulo in Brazil helps elucidate the impact of high levels of atmospheric carbon dioxide on human health. Research conducted by the Center for Research on Redox Processes in Biomedicine resulted in the detection of peroxymonocarbonate for the first time in human cells. Funder Fundação de Amparo à Pesquisa do Estado de São Paulo
20-Sep-2024 Deforestation in the Amazon is driven more by domestic demand than by the export market Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication A study by the University of São Paulo shows that expansion of cattle ranching to meet growing domestic demand has contributed more than any other driver to the elimination or degradation of the Amazon’s original vegetation, followed by expanding croplands and urbanization. Journal Nature Sustainability Funder Fundação de Amparo à Pesquisa do Estado de São Paulo
19-Sep-2024 Vegans’ intake of protein and essential amino acids is adequate but ultra-processed products are also needed Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication The study concluded that textured soy protein and plant-based protein supplements were the main ultra-processed products determining adequate protein intake for Brazilian vegans. The research involved 774 men and women who followed a vegan diet in Brazil. Journal JAMA Network Open Funder Fundação de Amparo à Pesquisa do Estado de São Paulo
18-Sep-2024 Study identifies possible novel species in fish genus endemic to Neotropics Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication Through morphological and molecular analysis of material collected from rivers in Brazil's Northeast region, the researchers are extending their knowledge of the evolutionary history of South American darters in the genus Characidium. Journal Systematics and Biodiversity Funder Fundação de Amparo à Pesquisa do Estado de São Paulo
16-Sep-2024 Breakthrough study reveals how mutant p53 protein converts other proteins into cancer drivers Instituto Nacional de Ciência e Tecnologia de Biologia Estrutural e Bioimagem (INBEB) Peer-Reviewed Publication Brazilian researchers from UFRJ and INBEB uncover how mutant p53, a key tumor suppressor, transforms proteins like p63 and p73 into cancer drivers via amyloid aggregation. Published in Communications Chemistry, the study also highlights heparin's potential to inhibit these harmful aggregates, offering a new approach for targeting aggressive cancers like glioblastoma. The findings open avenues for developing therapies to combat cancer at its molecular roots. Journal Communications Chemistry Funder Brazilian Council for Scientific and Technological Development (CNPq), Carlos Chagas Filho Foundation for Research Support (FAPERJ)